Soft laser desorption is laser desorption of large molecules that results in ionization without fragmentation. "Soft" in the context of ion formation means forming ions without breaking chemical bonds. "Hard" ionization is the formation of ions with the breaking of bonds and the formation of fragment ions.
Matrix-assisted laser desorption/ionization Surface-enhanced laser desorption/ionization Mass spectrometry Nitrogen laser Rapid Communications in Mass Spectrometry Synthetic polymer Analytical Chemistry (journal) Nd:YAG laser Koichi Tanaka Nobel Foundation Nanoparticle Biomolecule Ionization Glycerol Chemical bond Cobalt Nobel Prize in Chemistry Ion Laser
